Malignant melanoma (MM) is a highly malignant tumor of melanocytes, with increasing mortality rate and incidence rate in recent years.Although the treatments with targeted therapies and immune checkpoint inhibitors have significantly improved survival in advanced MM, tolerance and futile treatment are cards still the problems in the management of M
Berberis aetnensis C.Presl (Berberidaceae) is a bushy-spiny shrub common on Mount Etna (Sicily).We demonstrated that the alkaloid extract of roots of B.aetnensis C.Presl contains prevalently berberine and berbamine, possesses antimicrobial properties, and was able to counteract the upregulation evoked by glutamate of tissue transglutaminase in prim
Pasta, a cards Mediterranean diet staple, enhances well-being when enriched with healthy ingredients like durum wheat-germ (WG) and wheat-bran (WB).We studied the nutritional and clinical responses to four experimental pastas (EP1-EP4) made with de-oiled WG, WB, and microencapsulated durum wheat-oil (mWO), compared to a control pasta of water and s
Abstract LEAVE IN CONDITIONER UNSCENTED Background Full-thickness cartilage defects have a significant impact on the function of joints in young adults, and the treatment of cartilage defects has been a challenge, as cartilage tissue is an avascular tissue.This study aimed to compare the clinical and radiological outcomes of Biphasic Cartilage Repa
This paper investigates the synthesis and characterization of eco-friendly piezoelectric composite thin films composed of chitosan LEAVE IN CONDITIONER UNSCENTED and Ln2O3-doped Na0.5Bi0.5TiO3-BaTiO3 (NBT-BT) nanoparticles.The films were fabricated using a solution-casting technique, successfully embedding the particles into the chitosan matrix, wh